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Carbon dots-based fluorescence sensor for two-photon imaging of pH in diabetic mice
《化学科学与工程前沿(英文)》 2023年 第17卷 第3期 页码 298-306 doi: 10.1007/s11705-022-2212-9
ZHU Xiaoqin, QIAN Ying, LU Zhifeng
《化学科学与工程前沿(英文)》 2007年 第1卷 第4期 页码 381-384 doi: 10.1007/s11705-007-0069-6
关键词: 2-arylvinyl trans-vinylene character effective fluorescence push-core-pull-core-push
荧光碳点的快速宏量制备及多功能应用 Article
王丹,王志勇,詹求强,蒲源,王洁欣,Neil R. Foster,戴黎明
《工程(英文)》 2017年 第3卷 第3期 页码 402-408 doi: 10.1016/J.ENG.2017.03.014
荧光纳米材料在化学传感、生物成像及光电器件等领域具有重要应用前景,其合成方法的研究得到广泛关注。我们采用柠檬酸和乙二胺作为原料,在150 ℃、常压的相对温和条件下,通过“一锅法”反应制备了氮掺杂荧光碳点。所得荧光碳点光学带隙为3.4 eV,在单光子或双光子激发下呈现出明亮的荧光,且荧光发射波长稳定(λ = 450 nm)。基于荧光碳点低细胞毒性和长荧光寿命的优势,实现了荧光碳点作为离体肿瘤细胞(HeLa 细胞) 标记和荧光寿命成像探针的应用,获得了高对比度的荧光寿命成像结果。通过将所得荧光碳点与普通油墨混合制备均匀分散的荧光墨水,可用于普通纸张及其他基材( 如柔性塑料薄膜、纺织品、衣服) 的荧光图案化,为固态荧光传感、荧光防伪标记和可穿戴光电子设备应用研究提供了基础。
Yongqing Zhou, Xin Wang, Wei Zhang, Bo Tang, Ping Li
《化学科学与工程前沿(英文)》 2022年 第16卷 第1期 页码 4-33 doi: 10.1007/s11705-021-2041-2
关键词: bioactive molecules fluorescent probes in living cells and in vivo review
A survey of photon mapping state-of-the-art research and future challenges
Chun-meng KANG,Lu WAN,Yan-ning XU,Xiang-xu MENG
《信息与电子工程前沿(英文)》 2016年 第17卷 第3期 页码 185-199 doi: 10.1631/FITEE.1500251
关键词: Global illumination Photon mapping Radiance estimation Photon relaxation Progressive photon mapping
黄志洵
《中国工程科学》 2002年 第4卷 第1期 页码 54-63
论述了光波和物质波的波粒二象性理论的发展,讨论了该理论的存留问题。认为光子的静质量和光子的内部结构仍是科学中的关键性疑点。指出,虽然波粒二象性成立的前提是波长足够小,但在现有理论中却提不出一条清晰的界线。讨论了光波和电磁波是物质还是物质属性的问题。提出了对de Broglie波超光速相速的疑问。分析表明,如何建立电磁脉冲的粒子形象的问题仍需解决。此外,探讨了当电磁脉冲以超光速传播时相对论是否受破坏。最后,讨论了消失波的粒子性和虚光子问题。
evaluation of renal function using diffusion weighted imaging and diffusion tensor imaging in type 2
null
《医学前沿(英文)》 2014年 第8卷 第4期 页码 471-476 doi: 10.1007/s11684-014-0365-8
This work aims to estimate the value of diffusion weighted imaging (DWI) and diffusion tensor imaging (DTI) in detecting early-stage kidney injury in type 2 diabetic patients with normoalbuminuria (NAU) versus microalbuminuria (MAU) prospectively. A total of 30 T2DM patients with normal kidney function were recruited and assigned to the NAU group (n = 14) or MAU group (n= 16) according to 8 h overnight urinary albuminuria excretion rate (AER) results. A contemporary cohort of health check-up recipients were included as controls (n = 12). DWI and DTI scans were performed on bilateral kidney using SE single-shot EPI, and apparent diffusion coefficient (ADC) and fractional anisotropy (FA) of the renal parenchyma was determined from ADC and FA maps of the three groups. ADC and FA values were compared among the three groups. According to DWI with a b value of 400 s/mm2, the MAU and NAU groups showed significantly lowered mean ADC values compared with the healthy controls (P<0.01). The mean ADC in the MAU group [(2.22±0.07)×10–3 mm2/s] was slightly lower than that of the NAU group [(2.31±0.22)×10–3 mm2/s], but this difference was not statistically significant (P>0.05). The FA value in the MAU group was higher than that in the control group (0.45±0.07 vs. 0.39±0.03, P = 0.004) but did not differ from that in the NAU group (0.42±0.03) (P>0.05). ADC and FA values may be more sensitive than urine AER in reflecting early-stage kidney injury and, hence, may facilitate earlier detection and quantitative evaluation of kidney injury in T2DM patients. Combined evaluation of ADC and FA values may provide a better quantitative approach for identifying diabetic nephropathy at early disease stages.
关键词: type 2 diabetes mellitus microalbuminuria diffusion weighted imaging diffusion tensor imaging early-stage kidney injury
In vivo imaging of hematopoietic stem cell development in the zebrafish
Panpan Zhang, Feng Liu
《医学前沿(英文)》 2011年 第5卷 第3期 页码 239-247 doi: 10.1007/s11684-011-0123-0
关键词:
hematopoietic stem cell
hematopoiesis
Anefficient quadrature demodulator for medical ultrasound imaging
Hao ZHOU,Yin-fei ZHENG
《信息与电子工程前沿(英文)》 2015年 第16卷 第4期 页码 301-310 doi: 10.1631/FITEE.1400205
关键词: B-mode ultrasound imaging Color flow imaging Quadrature demodulation Finite impulse response filter
光场成像技术:模型、标定、重建及应用 Review
Hao ZHU, Qing WANG, Jingyi YU
《信息与电子工程前沿(英文)》 2017年 第18卷 第9期 页码 1236-1249 doi: 10.1631/FITEE.1601727
关键词: 光场成像;全光函数;成像模型;标定;重建
Liangqian Tong, Ming Zhao, Shu Zhu, Jing Chen
《医学前沿(英文)》 2011年 第5卷 第4期 页码 379-387 doi: 10.1007/s11684-011-0162-6
关键词: nanoparticles superparamagnetic iron oxide targeted therapy molecular imaging cancer
《化学科学与工程前沿(英文)》 2022年 第16卷 第1期 页码 103-111 doi: 10.1007/s11705-021-2064-8
关键词: UDP-glucuronosyltransferase 1A8 fluorescent probe subtype selectivity fluorescence imaging
《医学前沿(英文)》 页码 993-1005 doi: 10.1007/s11684-023-0989-7
标题 作者 时间 类型 操作
Synthesis and characterization of 2,5-bis[4-(2-arylvinyl)phenyl]-1,3,4-oxadiazoles with two-photon fluorescence
ZHU Xiaoqin, QIAN Ying, LU Zhifeng
期刊论文
Recent advances in small molecule fluorescent probes for simultaneous imaging of two bioactive molecules
Yongqing Zhou, Xin Wang, Wei Zhang, Bo Tang, Ping Li
期刊论文
A survey of photon mapping state-of-the-art research and future challenges
Chun-meng KANG,Lu WAN,Yan-ning XU,Xiang-xu MENG
期刊论文
evaluation of renal function using diffusion weighted imaging and diffusion tensor imaging in type 2
null
期刊论文
邵永红:基于谐波的多光子扫描结构光照明超分辨显微成像(2022年12月9日)
2023年02月01日
会议视频
Synthesis and application of superparamagnetic iron oxide nanoparticles in targeted therapy and imaging
Liangqian Tong, Ming Zhao, Shu Zhu, Jing Chen
期刊论文
A highly selective fluorescent probe for real-time imaging of UDP-glucuronosyltransferase 1A8 in living
期刊论文